Transactions of the Institute of Measurement and Control

 

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Transactions of the Institute of Measurement and Control, Vol. 4, No. 2, 93-100 (1982)
DOI: 10.1177/014233128200400204

In-vivo measurement of blood flow using radionuclides

J.O. Rowan, PhD, CEng, MIEE, FinstP

Department of Clinical Physics and Bioengineering, Institute of Neurological Sciences, Glasgow

This paper reviews the fundamental basis of radionuclide tracer methods used in the investigation of the circulation. The various Xenon-133-clearance methods for the measurement of cerebral blood flow are described, and their advantages and limitations are indicated. An outline is also given of the use of corresponding tracer-clearance techniques in the determination of blood flow in liver and muscle. The potential advantages of short-lived positron-emitting radionuclides and positron-emission tomography are considered, and quantitative and qualitative non-diffusible radionuclide tracer methods are also discussed.


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